Catalyst development for organocatalytic hydrosilylation of aromatic ketones and ketimines MalkovAndrei Stewart-LiddonAngus J.P. McGeochGrant D. Ramirez-LopezPedro KocovskyPavel 2014 A new family of Lewis basic 2-pyridyl oxazolines have been developed, which can act as efficient organocatalysts for the enantioselective reduction of prochiral aromatic ketones and ketimines with trichlorosilane, a readily available and inexpensive reagent. 1-Isoquinolyl oxazoline, derived from mandelic acid, was identified as the most efficient catalyst of the series, capable of delivering high enantioselectivities in the reduction of both ketones (up to 94% ee) and ketimines (up to 89% ee).