Malkov, Andrei Stewart-Liddon, Angus J.P. McGeoch, Grant D. Ramirez-Lopez, Pedro Kocovsky, Pavel Catalyst development for organocatalytic hydrosilylation of aromatic ketones and ketimines A new family of Lewis basic 2-pyridyl oxazolines have been developed, which can act as efficient organocatalysts for the enantioselective reduction of prochiral aromatic ketones and ketimines with trichlorosilane, a readily available and inexpensive reagent. 1-Isoquinolyl oxazoline, derived from mandelic acid, was identified as the most efficient catalyst of the series, capable of delivering high enantioselectivities in the reduction of both ketones (up to 94% ee) and ketimines (up to 89% ee). Catalysis;Organocatalysis;Ketones;Ketimines;Chemical Sciences not elsewhere classified;Organic Chemistry 2014-08-08
    https://repository.lboro.ac.uk/articles/journal_contribution/Catalyst_development_for_organocatalytic_hydrosilylation_of_aromatic_ketones_and_ketimines/9389585