Stoop, Ralph L. Wipf, Mathias Muller, Steffen Bedner, Kristine Wright, Iain Martin, Colin J. Constable, Edwin C. Fanget, Axel Schonenberger, Christian Calame, Michel Implementing silicon nanoribbon field-effect transistors as arrays for multiple ion detection © 2016 by the author.Ionic gradients play a crucial role in the physiology of the human body, ranging from metabolism in cells to muscle contractions or brain activities. To monitor these ions, inexpensive, label-free chemical sensing devices are needed. Field-effect transistors (FETs) based on silicon (Si) nanowires or nanoribbons (NRs) have a great potential as future biochemical sensors as they allow for the integration in microscopic devices at low production costs. Integrating NRs in dense arrays on a single chip expands the field of applications to implantable electrodes or multifunctional chemical sensing platforms. Ideally, such a platform is capable of detecting numerous species in a complex analyte. Here, we demonstrate the basis for simultaneous sodium and fluoride ion detection with a single sensor chip consisting of arrays of gold-coated SiNR FETs. A microfluidic system with individual channels allows modifying the NR surfaces with self-assembled monolayers of two types of ion receptors sensitive to sodium and fluoride ions. The functionalization procedure results in a differential setup having active fluoride- and sodium-sensitive NRs together with bare gold control NRs on the same chip. Comparing functionalized NRs with control NRs allows the compensation of non-specific contributions from changes in the background electrolyte concentration and reveals the response to the targeted species. Chemical sensing;Nanoribbons;Sodium;Fluoride;Gold;Ion-sensitive field-effect transistors;ChemFETs;Chemical Sciences not elsewhere classified 2016-12-16
    https://repository.lboro.ac.uk/articles/journal_contribution/Implementing_silicon_nanoribbon_field-effect_transistors_as_arrays_for_multiple_ion_detection/9390080