2134/13935
Sanjitpal Singh
Sanjitpal
Singh
Mark Elsegood
Mark
Elsegood
Marc Kimber
Marc
Kimber
An Au(I)-catalysed allenamide cyclisation giving access to an α-vinyl-substituted tetrahydroisoquinoline building block
Loughborough University
2014
Alkaloids
Allenamide
Tetrahydroisoquinoline
Au(I) catalysis
Diastereoselective
Chemical Sciences not elsewhere classified
Organic Chemistry
2014-01-09 14:32:03
Journal contribution
https://repository.lboro.ac.uk/articles/journal_contribution/An_Au_I_-catalysed_allenamide_cyclisation_giving_access_to_an_-vinyl-substituted_tetrahydroisoquinoline_building_block/9390734
An Au(I)-catalysed intramolecular hydroarylation of an enantiopure allenamide has been achieved and has given access to a key α-vinyl- substititued tetrahydroisoquinoline. Additionally this has been accomplished in very high yield and high diastereoselectivity. © Georg Thieme Verlag Stuttgart · New York.