%0 Journal Article %A Jones, Ray %A Berthelot, Didier J.C. %A Iley, James N. %D 2009 %T An alkylation route to carbo- and heteroaromatic amino acids %U https://repository.lboro.ac.uk/articles/journal_contribution/An_alkylation_route_to_carbo-_and_heteroaromatic_amino_acids/9392210 %2 https://repository.lboro.ac.uk/ndownloader/files/17006045 %K Amino acid %K Non-proteinogenic %K Ephedrine glycinamide %K Glycine enolate %K Pyridylalanine %K Chemical Sciences not elsewhere classified %K Organic Chemistry %X Amino acids carrying aromatic carbo- and heterocycles in the side chain, such as naphthyl-, biphenyl- and pyridylalanines, have been prepared by alkylation of a glycine enolate with a haloalkyl carbocycle or heterocycle, with enantiomeric excess up to 87% using the ephedrine amide protocol. %I Loughborough University