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Steven M. Allin
Steven M.
Allin
Christopher I. Thomas
Christopher I.
Thomas
James E. Allard
James E.
Allard
Kevin J. Doyle
Kevin J.
Doyle
Mark Elsegood
Mark
Elsegood
A highly selective synthesis of the indolo[2,3-a]quinolizine ring system and application to natural product synthesis
Loughborough University
2006
Natural products
Heterocycles
Lactams
Asymmetric synthesis
Chemical Sciences not elsewhere classified
Organic Chemistry
2006-01-06 10:29:08
Journal contribution
https://repository.lboro.ac.uk/articles/journal_contribution/A_highly_selective_synthesis_of_the_indolo_2_3-a_quinolizine_ring_system_and_application_to_natural_product_synthesis/9393254
We present a facile and highly stereoselective approach to the indolo[2,3-a]quinolizine ring
system from a readily available, non-racemic chiral template. We demonstrate the potential for
application of this methodology to natural product synthesis through conversion of the
template to some representative indole alkaloids with high enantiomeric purity in both
enantiomeric series.