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Roger Smith
Roger
Smith
Superheated water: the ultimate green solvent for separation science
Loughborough University
2006
Superheated water
Extraction
Chromatography
Green solvent
Chemical Sciences not elsewhere classified
2006-07-07 17:06:21
Journal contribution
https://repository.lboro.ac.uk/articles/journal_contribution/Superheated_water_the_ultimate_green_solvent_for_separation_science/9394127
Normally, chromatographers regard water in reversed-phase chromatography as a largely inert diluent, which acts to weaken the “active organic modifier”, and as a “poor” solvent for most organic compounds, unless aided by ionisation. We rarely comment on its effect in separation science or consider if it has changeable properties that we can exploit. With a few exceptions, most liquid chromatography is carried out between 30 and 50°C, however, elevated temperature has a profound effect, both on the properties and separation power of water, that we are only just starting to exploit.