%0 Journal Article %A Smith, Roger %D 2006 %T Superheated water: the ultimate green solvent for separation science %U https://repository.lboro.ac.uk/articles/journal_contribution/Superheated_water_the_ultimate_green_solvent_for_separation_science/9394127 %2 https://repository.lboro.ac.uk/ndownloader/files/17008604 %K Superheated water %K Extraction %K Chromatography %K Green solvent %K Chemical Sciences not elsewhere classified %X Normally, chromatographers regard water in reversed-phase chromatography as a largely inert diluent, which acts to weaken the “active organic modifier”, and as a “poor” solvent for most organic compounds, unless aided by ionisation. We rarely comment on its effect in separation science or consider if it has changeable properties that we can exploit. With a few exceptions, most liquid chromatography is carried out between 30 and 50°C, however, elevated temperature has a profound effect, both on the properties and separation power of water, that we are only just starting to exploit. %I Loughborough University