2134/24395
Zhichao Chen
Zhichao
Chen
Xianglin Zhang
Xianglin
Zhang
Penghua Chen
Penghua
Chen
Wenchao Li
Wenchao
Li
Kui Zhou
Kui
Zhou
Lei Shi
Lei
Shi
Kang Liu
Kang
Liu
Changqing Liu
Changqing
Liu
3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials
Loughborough University
2017
Additive manufacturing
Multi-nozzle system
Ejection and extrusion
Droplet control
3D biomimetic scaffold
Mechanical Engineering not elsewhere classified
Mechanical Engineering
2017-03-13 12:13:15
Journal contribution
https://repository.lboro.ac.uk/articles/journal_contribution/3D_multi-nozzle_system_with_dual_drives_highly_potential_for_3D_complex_scaffolds_with_multi-biomaterials/9568361
Recently, additive manufacturing is one of the most focused research topics due to its explosive development, especially in
manufacturing engineering and medical science. In order to build 3D complex scaffolds with multi-biomaterials for clinical
application, a new 3D multi-nozzle system with dual-mode drives, i.e. ejection and extrusion was developed. In this paper,
much effort was made to gain fine control of droplet and excellent coordination during fabrication. Specifically, the parameters
that influence the size and stability of droplet most was intensively studied. Considering that the biomaterials used in the future
may have much difference in properties, the combination of parameters was investigated to facilitate the settings for certainsized
droplets, which are potentially eligible for bio-printing. The dispensing nozzles can work well both in independent and
convergent mode, which can be freely switched. Outstanding to the most currently used 3D bio-printing techniques, this system
can fabricate scaffolds with multi-materials of both low viscosity (by pneumatic dispensing) and high viscosity (through motor
extrusion). It is highly expected that this system can satisfy clinical application in the near future.