Alzheimer_WRM_2015.pdf (182.82 kB)
Alzheimer: nasal transplantation of microglia
conference contribution
posted on 2016-03-21, 10:27 authored by Claire Fabian, Yahaira Naaldijk, Alexandra StolzingAlexandra StolzingAlzheimer’s disease (AD) is an age-related neurodegenerative disease associated with the formation of amyloid plaques, [tau] aggregation and oxidative/inflammatory damage. Microglia play an important role in the early phase of the disease and are known to be involved in AD progression. Senescent microglia accumulate in AD causing inflammation, neuronal damage and increasing the A[beta] load. Microglia could be an attractive target for mesenchymal cell therapies (MSC).
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
12th International Symposium on the Neurobiology and Neuroendocrinology of Aging EXPERIMENTAL GERONTOLOGYVolume
68Pages
93 - 93 (1)Citation
FABIAN, C., NAALDIJK, Y. and STOLZING, A., 2015. Alzheimer: nasal transplantation of microglia. IN: Proceedings of 2014 12th International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria, 27 July-1 August 2014. Experimental Gerontology, 68, p.93.Publisher
© ElsevierVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2015Notes
This paper was accepted for publication in the journal Experimental Gerontology and the definitive published version is available at http://dx.doi.org/10.1016/j.exger.2015.01.010ISSN
0531-5565Publisher version
Language
- en
