MSSE accepted version 13.01.16.pdf (534.82 kB)
Arm and intensity-matched leg exercise induce similar inflammatory responses
journal contribution
posted on 2016-02-02, 12:50 authored by Christof LeichtChristof Leicht, Thomas A.W. Paulson, Vicky Goosey-TolfreyVicky Goosey-Tolfrey, Nicolette BishopNicolette BishopIntroduction: The amount of active muscle mass can influence the acute inflammatory response to exercise, associated with reduced risk for chronic disease. This may affect those restricted to upper body exercise, for example due to injury or disability. The purpose of this study was to compare the inflammatory responses for arm exercise and intensity-matched leg exercise.
Methods: Twelve male individuals performed three 45-min constant load exercise trials following determination of peak oxygen uptake for arm exercise (V[Combining Dot Above]O2peak A) and cycling (V[Combining Dot Above]O2peak C): (1) arm cranking exercise at 60%V[Combining Dot Above]O2peak A; (2) moderate cycling at 60%V[Combining Dot Above]O2peak C; and (3) easy cycling at 60%V[Combining Dot Above]O2peak A. Cytokine, adrenaline and flow cytometric analysis of monocyte subsets were performed before and up to 4h post exercise.
Results: Plasma IL-6 increased from resting concentrations in all trials, however, post exercise concentrations were higher for arm exercise (1.73+/-1.04pg[BULLET OPERATOR]mL-1) and moderate cycling (1.73+/-0.95pg[BULLET OPERATOR]mL-1) compared with easy cycling (0.87+/-0.41pg[BULLET OPERATOR]mL-1,P<0.04). Similarly, the plasma IL-1ra concentration in the recovery period was higher for arm exercise (325+/-139pg[BULLET OPERATOR]mL-1) and moderate cycling (316+/-128pg[BULLET OPERATOR]mL-1) when compared with easy cycling (245+/-77pg[BULLET OPERATOR]mL-1,P<0.04). Arm exercise and moderate cycling induced larger increases in monocyte numbers and larger increases of the classical monocyte subset in the recovery period than easy cycling (P<0.05). The post-exercise adrenaline concentration was lowest for easy cycling (P=0.04).
Conclusions: Arm exercise and cycling at the same relative exercise intensity induces a comparable acute inflammatory response; however, cycling at the same absolute oxygen uptake as arm exercise results in a blunted cytokine, monocyte and adrenaline response. Relative exercise intensity appears to be more important to the acute inflammatory response than modality, which is of major relevance for populations restricted to upper body exercise.
History
School
- Sport, Exercise and Health Sciences
Published in
Medicine and Science in Sports and ExerciseVolume
48Issue
6Pages
1161 - 1168Citation
LEICHT, C.A. ... et al, 2016. Arm and intensity-matched leg exercise induce similar inflammatory responses. Medicine and Science in Sports and Exercise, 48 (6), pp. 1161-1168.Publisher
Lippincott, Williams & Wilkins (© American College of Sports Medicine (ACSM))Version
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2016-06-30Notes
This is a non-final version of an article published in final form in LEICHT, C.A. ... et al, 2016. Arm and intensity-matched leg exercise induce similar inflammatory responses. Medicine and Science in Sports and Exercise, 48 (6), pp. 1161-1168.ISSN
0195-9131eISSN
1530-0315Publisher version
Language
- en