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Atmospheric pressure plasmas: generation and delivery of reactive oxygen species for biomedical applications
conference contribution
posted on 2015-05-21, 08:31 authored by Felipe IzaFelipe Iza, Kirsty McKay, Ding-Xin Liu, Ming-Zhe Rong, Michael G. KongReactive oxygen species (ROS) that can trigger biological responses are readily attainable in
atmospheric pressure plasma sources. Admixtures of oxygen and water can act as precursors for
the generation of these ROS and lead to the production of O, OH, O3, 1
O2, OOH and H2O2. The
dynamics and chemistry in these discharges is complex and result in intricate spatiotemporal
profiles of the species that cannot be accurately captured by zero dimensional analysis. Besides
fluxes of neutral ROS, ionic fluxes including anions are also observed. The high reactivity of most
of the ROS, however, limits their penetration into the treated sample and therefore encapsulation
of the ROS and/or triggering of a secondary chemistry is required for the plasma treatment to
reach beyond the first layers of biomolecules.
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
XXX International Conference on Ionized GasesCitation
IZA, F. ... et al., 2011. Atmospheric pressure plasmas: generation and delivery of reactive oxygen species for biomedical applications. IN: Proceedings of the XXX International Conference on Ionized Gases (ICPIG 2011), Belfast, UK, 28 August - 2 September 2011.Publisher
Queen's University BelfastVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2011Notes
This is a conference paper.Publisher version
Language
- en