File(s) not publicly available
Reason: This item is currently closed access.
Construction of macrocyclic thiodepsipeptides: synthesis of a nosiheptide 'southern hemisphere' model system
journal contributionposted on 08.01.2014 by Marc Kimber, Christopher J. Moody
Any type of content formally published in an academic journal, usually following a peer-review process.
A 20-membered macrocyclic thiodepsipeptide has been synthesized as a model for the southern hemisphere of nosiheptide, the key steps being assembly of an acyclic precursor by amide coupling of indole and thiazole fragments followed by formation of the thiolactone in the macrocyclization step.