Cycloaddition chemistry of allenamides

2014-01-10T13:47:10Z (GMT) by Patricia E. Standen Marc Kimber
Allenamides are electron deficient allenamine equivalents that can participate in a range of cycloaddition events giving rise to novel heterocycles and diverse molecular architectures contained within natural products. This review summarizes some of the recent research in this area, with particular reference to predicting the stereochemical outcomes of such transformations and highlighting recent applications of allenamides in cycloaddition transformations which showcase the utility of this under-utilized synthon.