Effect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation
journal contributionposted on 08.03.2016 by Deborah K. Dulson, Nicolette Bishop
Any type of content formally published in an academic journal, usually following a peer-review process.
This study investigated the effect of caffeine on antigen-stimulated lymphocyte activation. Six males rested for 3.5 h after ingesting 0 (PLA), 2, or 6 (6CAF) mg·kg−1 body mass of caffeine. The number of antigen-stimulated NK CD69+ cells increased in 6CAF at 1 h compared with PLA (P = 0.021). Caffeine did not influence the number of antigen-stimulated CD69+ T cells or the geometric mean fluorescence intensity expression of CD69 on antigen-stimulated lymphocytes, suggesting caffeine has little effect on antigen-stimulated lymphocyte activation.
- Sport, Exercise and Health Sciences