Loughborough University
Browse

File(s) under permanent embargo

Reason: This item is currently closed access.

End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation

journal contribution
posted on 2014-07-22, 11:38 authored by Salvatore Mascia, Patrick L. Heider, Haitao Zhang, Richard Lakerveld, Brahim BenyahiaBrahim Benyahia, Paul I. Barton, Richard D. Braatz, Charles L. Cooney, James M.B. Evans, Timothy F. Jamison, Klavs F. Jensen, Allan S. Myerson, Bernhardt L. Trout
A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot-scale plant used a novel route that incorporated many advantages of continuous-flow processes to produce active pharmaceutical ingredients and the drug product in one integrated system.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

Angewandte Chemie - International Edition

Volume

52

Issue

47

Pages

12359 - 12363

Citation

MASCIA, S. ... et al, 2013. End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation. Angewandte Chemie - International Edition, 52 (47), pp.12359-12363.

Publisher

© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Version

  • VoR (Version of Record)

Publication date

2013

Notes

This paper is closed access.

ISSN

1433-7851

eISSN

1521-3773

Language

  • en

Usage metrics

    Loughborough Publications

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC