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MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite

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conference contribution
posted on 2017-01-27, 16:41 authored by Hakan Nygren, Per Malmberg, Yang LiuYang Liu
Healing of rat tibia after intramedullary implantation of MgO was analysed by Environmental Scanning Electron Microscopy (ESEM) and Energy-Dispersive X-ray spectroscopy (EDX). The results indicated the formation of hydroxyl-apatite (HA) in the entire intramedullary space after 1 week of healing. Then, corroded Mg, MgO and MgCO3 were incubated with DMEM in vitro for 24 h and the surface of the material was analysed by EDX and Time-of-Flight Secondary Ion Mass (ToF-SIMS). The chemical analysis of the Mg corrosion products indicate that HA is formed at the material surface and that MgCO3 was an efficient catalyzer of HA formation.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

Materials Science Forum

Volume

879

Pages

1404 - 1407

Citation

NYGREN, H., MALMBERG, P. and LIU, Y., 2016. MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite. IN: Sommitsch, C. ... et al. (eds). THERMEC 2016, 9th International Conference on Processing & Manufacturing of Advanced Materials, Graz, Austria, 29th May - 3rd June 2016. Trans Tech Publications, pp. 1404-1407.

Publisher

© Trans Tech Publications

Version

  • AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2016

Notes

This is a conference paper. It was published in the series Materials Science Forum and the definitive version is available at: http://www.scientific.net/MSF.879.1404

ISBN

9783035711295

ISSN

0255-5476

eISSN

1662-9752

Book series

Materials Science Forum;879

Language

  • en

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