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Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
journal contribution
posted on 2017-11-17, 11:38 authored by Mira Soni, Martin Orrell, Stephan Bandelow, Andrew Steptoe, Snorri Bjorn Rafnsson, Eleonora d'Orsi, Andre Junqueira Xavier, Eef HogervorstEef HogervorstBackground: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes in people with dementia. Methods: Data from 11,391 men and women (aged ≥50) were obtained from the English Longitudinal Study of Ageing cohort. Assessments were carried out at baseline (2002–2003) and at biannual follow-ups (2004–2013). Results: Older adults who carried out moderate to vigorous activity at least once per week had a 34%–50% lower risk for cognitive decline and dementia over an 8–10 year follow-up period. From pre- to post-dementia diagnosis, those who decreased PA levels had a larger decrease in immediate recall scores, compared to those who maintained or increased PA levels (analyses were adjusted for changes in physical function). Conclusion: PA was associated with cognitive outcomes in a dose-dependent manner. Reduction in PA after diagnosis was associated with accelerated cognitive decline and maintaining PA may reduce symptom progression in dementia.
Funding
This study was carried out as part of PRIDE (PRomoting Independence in DEmentia). PRIDE was funded by the UK Economic and Social Research Council (ESRC) (Grant ES/L001802/1).
History
School
- Sport, Exercise and Health Sciences
Published in
Aging and Mental HealthPages
1 - 7Citation
SONI, M. ...et al., 2017. Physical activity pre- and post-dementia: English Longitudinal Study of Ageing. Aging and Mental Health, 23 (1), pp.15-21.Publisher
© Taylor & FrancisVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc/4.0/Acceptance date
2017-09-30Publication date
2017Notes
This is an Accepted Manuscript of an article published by Taylor & Francis in Aging and Mental Health on 17 Oct 2017, available online: https://doi.org/10.1080/13607863.2017.1390731.ISSN
1360-7863eISSN
1364-6915Publisher version
Language
- en