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Prevalence and predictors of age related macular degeneration in the population of Punjab: North Indian age related macular degeneration epidemiology and molecular genetic study (NI-ARMEMS)
journal contribution
posted on 2018-11-30, 15:56 authored by Ritu Sharma, Kanchan Mehta, Jasvinder Singh Bhatti, Sarabjit MastanaSarabjit Mastana, Monica Singh, Puneetpal SinghBackground: Age related macular degeneration (AMD) is an ocular disease that is threatening
elderly population of Punjab for vision impairment and blindness. Comprehensive understanding of
the susceptible factors still remains to be explored in this region.
Objective: To examine the risk variables which are independently associated with the risk of AMD
along with the investigation of its prevalence in the population of Punjab.
Methods: A case-control study by design involved 416 subjects (cases; 219, controls; 197) of age
ranging from 45 to 75 years. Various risk factors were investigated for their role in consenting and
confirmed AMD subjects along with controls.
Results: In the univariate full factorial regression analysis, advancing age (≥66years), being a woman,
diastolic blood pressure (DBP) (>80mmHg), cigarette smoking, alcohol drinking, body mass index
(BMI) (23-29.9Kgm-2
and ≥30Kgm-2
), sedentary life style, total cholesterol (>200mg/dl), low density
lipoproteins (>100mg/dl), high density lipoproteins (≥40mg/dl), non-vegetarian diet and positive
family history were found to be risky determinants. Multivariable stepwise regression analysis
revealed age ≥66 years, DBP > 80mmHg, alcohol drinking and smoking as independent predictors for
the risk of AMD.
Conclusion: Considerable prevalence of dry AMD (20.5%) is evident in the population of Punjab
which is mediated independently by age (≥66 years), DBP (>80 mmHg), alcohol drinking and
smoking.
History
School
- Sport, Exercise and Health Sciences
Published in
International journal of health sciences and researchVolume
8Issue
10Pages
1 - 8Citation
SHARMA, R. ... et al., 2018. Prevalence and predictors of age related macular degeneration in the population of Punjab: North Indian age related macular degeneration epidemiology and molecular genetic study (NI-ARMEMS). International journal of health sciences and research, 8(10), pp. 1-8.Publisher
© International Journal of Health Sciences and ResearchVersion
- VoR (Version of Record)
Acceptance date
2018-10-07Publication date
2018-10-01Notes
This paper is open access, users shall have the right to "read, download, copy, distribute, print, search, or link" to the full text.ISSN
2249-9571Publisher version
Language
- en