Mitchell et al japplphysiol.01082.2017.pdf (15.72 MB)
The combined effect of sprint interval training and blood flow restriction on critical power, capillary growth and mitochondrial proteins in trained cyclists
journal contribution
posted on 2018-12-18, 11:51 authored by Emma A. Mitchell, Neil MartinNeil Martin, Mark Turner, Conor W. Taylor, Richard FergusonRichard FergusonSprint interval training (SIT) combined with post-exercise blood-flow restriction (BFR) is a
novel method to increase maximal oxygen uptake (V̇ O2max) in trained individuals, and also
provides a potent acute stimulus for angiogenesis and mitochondrial biogenesis. The efficacy
to enhance endurance performance has however yet to be demonstrated. 21 trained male
cyclists (V̇ O2max; 62.8 ± 3.7 ml.min-1
.kg-1
) undertook 4 weeks of SIT (repeated 30 sec
maximal sprints) either alone (CON; n = 10) or with post-exercise BFR (n = 11). Before and
after training V̇ O2max, critical power (CP) and Wʹ were determined and muscle biopsies
obtained for determination of skeletal muscle capillarity and mitochondrial protein content.
CP increased (P = 0.001) by a similar extent following CON (287 ± 39 W to 297 ± 43 W)
and BFR (296 ± 40 W to 306 ± 36 W). V̇ O2max increased following BFR by 5.9% (P = 0.02)
but was unchanged after CON (P = 0.56). All markers of skeletal muscle capillarity and
mitochondrial protein content were unchanged following either training intervention. In
conclusion, 4 weeks of SIT increased CP, however this was not enhanced further with BFR.
SIT was not sufficient to elicit changes in skeletal muscle capillarity and mitochondrial
protein content with or without BFR. However, we further demonstrate the potency of
combining BFR with SIT to enhance V̇ O2max in trained individuals.
History
School
- Sport, Exercise and Health Sciences
Published in
Journal of Applied PhysiologyVolume
126Issue
1Pages
51-59Citation
MITCHELL, E.A. ... et al., 2019. The combined effect of sprint interval training and blood flow restriction on critical power, capillary growth and mitochondrial proteins in trained cyclists. Journal of Applied Physiology, 126(1), pp. 51-59.Publisher
© American Physiological SocietyVersion
- AM (Accepted Manuscript)
Publisher statement
This paper was accepted for publication in the journal Journal of Applied Physiology, and the definitive published version is available at https://doi.org/10.1152/japplphysiol.01082.2017Acceptance date
2018-10-14Publication date
2019-01-09Copyright date
2019ISSN
8750-7587eISSN
1522-1601Publisher version
Language
- en