The reactions of codeinone and hydroxycodeinone

2018-12-14T14:42:58Z (GMT) by Mohammad U. Valhari
Derivatives of Diels-Alder adducts of thebaine and of 14-hydroxy codeinone provide some of the most potent analgesics in the morphine-thebaine group of alkaloids. As an extension to the range of available compounds, the preparation of further modified thebaines and 14-hydroxy codeinone was investigated. [Continues.]

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