Thesis-2002-Krintel.pdf (5.22 MB)
Triorganogermanes as non-toxic reagents in radical reactions
thesis
posted on 2018-11-14, 16:38 authored by Sussie L. KrintelTributyltin hydride (TBTH) has proven to be an extremely useful synthetic reagent
which has been widely used for generating free radicals, is largely responsible for the
large increase in the use of free radicals in organic synthesis and is the reagent of
choice for many researchers. However, the tin residues are highly toxic and difficult to
separate from reaction mixtures which precludes the use of tributyltin hydride in the
pharmaceutical industry. In this project, triorganogermanium compounds have been
investigated as possible alternatives to tin-based radical mediators. [Continues.]
Funding
Loughborough University. GlaxoSmithKline plc.
History
School
- Science
Department
- Chemistry
Publisher
© Sussie L. KrintelPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2002Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Doctor of Philosophy at Loughborough University.Language
- en