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Atmospheric pressure plasmas: generation and delivery of reactive oxygen species for biomedical applications

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conference contribution
posted on 21.05.2015 by Felipe Iza, Kirsty McKay, Ding-Xin Liu, Ming-Zhe Rong, Michael G. Kong
Reactive oxygen species (ROS) that can trigger biological responses are readily attainable in atmospheric pressure plasma sources. Admixtures of oxygen and water can act as precursors for the generation of these ROS and lead to the production of O, OH, O3, 1 O2, OOH and H2O2. The dynamics and chemistry in these discharges is complex and result in intricate spatiotemporal profiles of the species that cannot be accurately captured by zero dimensional analysis. Besides fluxes of neutral ROS, ionic fluxes including anions are also observed. The high reactivity of most of the ROS, however, limits their penetration into the treated sample and therefore encapsulation of the ROS and/or triggering of a secondary chemistry is required for the plasma treatment to reach beyond the first layers of biomolecules.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

XXX International Conference on Ionized Gases

Citation

IZA, F. ... et al., 2011. Atmospheric pressure plasmas: generation and delivery of reactive oxygen species for biomedical applications. IN: Proceedings of the XXX International Conference on Ionized Gases (ICPIG 2011), Belfast, UK, 28 August - 2 September 2011.

Publisher

Queen's University Belfast

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2011

Notes

This is a conference paper.

Language

en

Location

Belfast, UK

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