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Computational modelling of mechanical behavior of biological tissues for biomedical applications

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conference contribution
posted on 22.05.2017, 09:10 by Simin Li, Yang Liu, Juan Du, Begum Zeybek, Lorenzo Zani, Mark Lewis, Vadim Silberschmidt
Computational modelling of biomedical applications has gained significant momentum in recent years, in part to meet demands related to recent technical advancements in manufacturing of personalized biomedical equipment. However, our understanding of mechanics of biological tissues, their properties and performance as well as their interaction with biomedical equipment still remains limited. This is a result of multiple factors, most important being a hierarchical and heterogeneous nature of biological tissues, non-trivial loading and environmental conditions to which they are exposed as well as multi-disciplinary nature of the systems involved. This paper presents an overview of the latest research activities and achievements in the area of mechanics of biomaterials and tissues at Loughborough University, UK. It covers various types of biological materials and tissues - both hard (bones) and soft (muscles, etc.) - that have been studied in previous studies [1-4] at various spatial and temporal domains. These studies laid a foundation for development and implementation of advanced computational modelling of mechanics of these biological tissues at different stages (healthy, diseased and traumatic conditions) and for several areas of biomedical applications (injury prevention, wound care and rehabilitation). Performed numerical simulations, on the one hand, elucidate processes of deformation of biological tissues and, on the other hand, provide solutions for design and optimization of medical and rehabilitation procedures and devices. This work underpins a unique partnership between engineers, clinics and rehabilitation centres in UK aiming to transfer the latest scientific and technological advancements into personalized biomedical applications using computational schemes and tools.

History

School

  • Sport, Exercise and Health Sciences

Published in

ECCOMAS Congress 2016 - Proceedings of the 7th European Congress on Computational Methods in Applied Sciences and Engineering

Volume

1

Pages

1940 - 1949

Citation

LI, S. ...et al., 2016. Computational modelling of mechanical behavior of biological tissues for biomedical applications. IN: Papadrakakis, M. ...et al. (eds.) VII European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2016), Crete, June 5-10th, Vol 1, pp. 1940-1949.

Publisher

European Community on Computational Methods in Applied Sciences (ECCOMAS)

Version

NA (Not Applicable or Unknown)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2016

Notes

This conference paper is published with kind permission of the conference organisers.

ISBN

9786188284401

Language

en

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