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Spreading of blood over porous substrate: Dried blood spots sampling [Abstract]

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conference contribution
posted on 07.07.2017 by Craig Chao, Diganta Das, Victor Starov
Dried blood spot (DBS) sampling is a method of blood collection, transportation and storage which has been investigated and used over the recent decades [1], [2]. The applications of DBS have been well developed in different area, such as, newborn screening, preclinical test, pharmacokinetic (PK), toxicokinetic (TK) and therapeutic drug monitoring (TDM). The process of dried blood spots (DBS) sampling involves simultaneous spreading and penetration into a porous filter paper with subsequent evaporation and drying. The spreading/imbibition kinetic of blood, which is a non-Newtonian fluid, over different porous substrate is investigated from both experimental and theoretical points of view.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

The 6th APS International PharmSci Conference 2015, Nottingham, UK

Citation

CHAO, T-C., DAS, D.B. and STAROV, V., 2015. Spreading of blood over porous substrate: Dried blood spots sampling. Presented at the 6th APS International PharmSci Conference 2015, Nottingham, 7-9th September.

Publisher

© the Authors. Published by Academy of Pharmaceutical Sciences of Great Britain

Version

SMUR (Submitted Manuscript Under Review)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This is an abstract of a conference paper.

Language

en

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