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Structured biodegradable microparticles produced using glass microfluidic flow focussing devices

conference contribution
posted on 09.12.2014 by Ekanem Ekanem, Goran Vladisavljevic
Herein is reported the production of biodegradable poly (lactic acid) (PLA) and poly (lactic-co-glycolic acid) (PLGA) particles having modifiable internal and surface microstructures via single step emulsification using microfabricated 3D (axisymmetric) flow focusing glass capillary microfluidic devices and subsequent solvent evaporation. Controlled production of emulsion droplets was achieved and the morphology of particles produced after evaporation was investigated to ascertain its effect on hydrophobic drug encapsulation and release.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2014)

Pages

971 - 973

Citation

EKANEM, E.E. and VLADISAVLJEVIC, G.T., 2014. Structured biodegradable microparticles produced using glass microfluidic flow focussing devices. IN: Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), 26th-30th October 2014, San Antonio, Texas, USA. CBMS, pp. 971-973.

Publisher

© Chemical and Biological Microsystems Society (CBMS)

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2014

Notes

This conference paper is closed access.

ISBN

978097980647

Language

en

Location

San Antonio, Texas, USA

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