Correction of refraction induced distortion in optical coherence tomography corneal reconstructions for volume deformation measurements

In this project, the depth-resolved full-field deformation of the porcine cornea under changing intraocular pressure was investigated by performing digital volume correlation (DVC) on the reconstructed volume images generated through swept source optical coherence tomography (SS-OCT). Posterior inflation test of porcine cornea sample for two load steps were performed and the distribution patterns of displacement and strain fields were produced. The error sources for the measurements were analyzed. The refraction induced OCT image distortion is a main error source for the measurement results. Then, a methodology was developed to correct the OCT distortion based on the Fermat’s principle.