DESIGNER MICROPARTICLES PRODUCED FROM GLASS MICROFLUIDIC DEVICES FOR DRUG DELIVERY.pdf (27.9 kB)
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Designer microparticles produced from glass microfluidic devices for drug delivery

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conference contribution
posted on 24.03.2015, 11:34 by Ekanem Ekanem, Goran VladisavljevicGoran Vladisavljevic
Methods for the manufacture of monodispersed emulsions which serve as templates for the production of microspheres used in drug encapsulation are being increasingly explored. This is due to the fact that such uniform emulsions, which are more stable, bring about microparticles which possess higher drug encapsulation efficiencies and more predictable release profiles. In this work, 3D (axisymmetric) flow focusing glass capillary microfluidic devices, pioneered by Utada et al. (2005), have been used for the generation of monodispersed emulsion droplets. These emulsions served as precursors for the production of microspheres with varying controllable surface and internal microstructure. Unique video images of droplet generation and microstructural images of microparticles together with drug release profiles from produced particles were obtained and would be presented.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

5th Annual Health & Wellbeing Research Conference

Citation

EKANEM, E. E. and VLADISAVLJEVIC, G. T., 2015. Designer microparticles produced from glass microfluidic devices for drug delivery. 5th Annual Health & Wellbeing Research Conference, Loughborough, February 2015. Abstract only.

Publisher

Loughborough University (© the authors)

Version

NA (Not Applicable or Unknown)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This is a conference abstract delivered at the 5th Annual Loughborough University Health Research Conference: http://luhealthconference.co.uk/

Language

en

Location

Loughborough

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