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Estimating glucose diffusivities in electrospun fibers using diffusion cell experiments and image processing

conference contribution
posted on 2015-10-30, 16:17 authored by Shuai Wang, Vibudh Agrawal, Diganta DasDiganta Das, Stella GeorgiadouStella Georgiadou
Electrospinning is a common technique, which is applied for fabrication of scaffold for tissue engineering bioreactors. For making the scaffolds with desired morphology, a thorough understanding of the effects of the key parameters on nutrient transport in the scaffold are needed. Furthermore, it is necessary to have methods that predict the nutrient transport behavior. To address these issues partially, we prepare electro-spun polycaprolactone (PCL) scaffolds with different pore morphology by using different electrospinning duration and polymer solution flow rate. . Subsequently, the glucose diffusivities of these scaffolds imbibed in cell culture medium (CCM) and water are then measured. It is observed that the electrospinning process is reproducible and fiber-fiber space and fiber diameter are both increased with higher PCL flow rate. The fiber-fiber distance and fiber diameter are also slightly increased if the flow rate is increased by the usage of two syringes for injecting the polymer solution instead of a single cylinder.



  • Aeronautical, Automotive, Chemical and Materials Engineering


  • Chemical Engineering

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InterPore-PMPM UK Chapter Kick-off meeting


WANG, S. ... et al, 2015. Estimating glucose diffusivities in electrospun fibers using diffusion cell experiments and image processing. Presented at: InterPore-PMPM UK Chapter Formation Meeting, 25th August 2015, University of Manchester.


  • AM (Accepted Manuscript)

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This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

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This is a conference presentation


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The University of Manchester

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