Loughborough University
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Fully automatic lesion boundary detection in ultrasound breast images

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conference contribution
posted on 2010-07-15, 16:12 authored by Moi Hoon Yap, Eran Edirisinghe, Helmut Bez
We propose a novel approach to fully automatic lesion boundary detection in ultrasound breast images. The novelty of the proposed work lies in the complete automation of the manual process of initial Region-of-Interest (ROI) labeling and in the procedure adopted for the subsequent lesion boundary detection. Histogram equalization is initially used to preprocess the images followed by hybrid filtering and multifractal analysis stages. Subsequently, a single valued thresholding segmentation stage and a rule-based approach is used for the identification of the lesion ROI and the point of interest that is used as the seed-point. Next, starting from this point an Isotropic Gaussian function is applied on the inverted, original ultrasound image. The lesion area is then separated from the background by a thresholding segmentation stage and the initial boundary is detected via edge detection. Finally to further improve and refine the initial boundary, we make use of a state-of-the-art active contour method (i.e. gradient vector flow (GVF) snake model). We provide results that include judgments from expert radiologists on 360 ultrasound images proving that the final boundary detected by the proposed method is highly accurate. We compare the proposed method with two existing stateof- the-art methods, namely the radial gradient index filtering (RGI) technique of Drukker et. al. and the local mean technique proposed by Yap et. al., in proving the proposed method’s robustness and accuracy.



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YAP, M.H., EDIRISINGHE, E.A. and BEZ, H.E., 2007. Fully automatic lesion boundary detection in ultrasound breast images. IN: Pluim, J.P.W. and Reinhardt, J.M. (eds), Medical Imaging 2007: Image Processing, Proc. of SPIE, 6512, 65123I, 9pp.


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Copyright 2007 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. This paper can also be found at: http://dx.doi.org/10.1117/12.708625


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