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Structured biodegradable microparticles produced using glass microfluidic flow focussing devices
conference contribution
posted on 2014-12-09, 11:31 authored by Ekanem Ekanem, Goran VladisavljevicGoran VladisavljevicHerein is reported the production of biodegradable poly (lactic acid) (PLA) and poly (lactic-co-glycolic acid) (PLGA) particles having modifiable internal and surface microstructures via single step emulsification using microfabricated 3D (axisymmetric) flow focusing glass capillary microfluidic devices and subsequent solvent evaporation. Controlled production of emulsion droplets was achieved and the morphology of particles produced after evaporation was investigated to ascertain its effect on hydrophobic drug encapsulation and release.
History
School
- Aeronautical, Automotive, Chemical and Materials Engineering
Department
- Chemical Engineering
Published in
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2014)Pages
971 - 973Citation
EKANEM, E.E. and VLADISAVLJEVIC, G.T., 2014. Structured biodegradable microparticles produced using glass microfluidic flow focussing devices. IN: Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), 26th-30th October 2014, San Antonio, Texas, USA. CBMS, pp. 971-973.Publisher
© Chemical and Biological Microsystems Society (CBMS)Version
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2014Notes
This conference paper is closed access.ISBN
978097980647Publisher version
Language
- en
