File(s) under permanent embargo
Reason: This item is currently closed access.
Structured biodegradable microparticles produced using glass microfluidic flow focussing devices
conference contributionposted on 09.12.2014, 11:31 by Ekanem Ekanem, Goran Vladisavljevic
Herein is reported the production of biodegradable poly (lactic acid) (PLA) and poly (lactic-co-glycolic acid) (PLGA) particles having modifiable internal and surface microstructures via single step emulsification using microfabricated 3D (axisymmetric) flow focusing glass capillary microfluidic devices and subsequent solvent evaporation. Controlled production of emulsion droplets was achieved and the morphology of particles produced after evaporation was investigated to ascertain its effect on hydrophobic drug encapsulation and release.
- Aeronautical, Automotive, Chemical and Materials Engineering
- Chemical Engineering