Supplementary information files for "Kidney Beam-A Cost-Effective Digital Intervention to Improve Mental Health"

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posted on 2025-03-31, 09:03 authored by Sharlene A Greenwood, Juliet Briggs, Christy Walklin, Emmanuel Mangahis, Hannah ML Young, Ellen M Castle, Roseanne E Billany, Elham Asgari, Sunil Bhandari, Nicolette BishopNicolette Bishop, Kate Bramham, James O Burton, Jackie Campbell, Joseph Chilcot, Nicola Cooper, Vashist Deelchand, Matthew PM Graham-Brown, Lynda Haggis, Alexander Hamilton, Mark Jesky, Philip A Kalra, Pelagia Koufaki, Kieran McCafferty, Andrew C Nixon, Helen Noble, Zoe L Saynor, Maarten W Taal, James Tollitt, David C Wheeler, Thomas J Wilkinson, Hannah Worboys, Jamie Macdonald

Supplementary files for article " Kidney Beam-A cost-effective digital intervention to improve mental health

Introduction: There is inequity in the provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention (DHI) in CKD.

Methods: In a single-blind, 11 center, randomized controlled trial, 340 adult participants with CKD were randomly assigned to either the Kidney BEAM physical activity DHI or a waitlist control. This study assessed the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between intervention and control groups at 6-months, and cost-effectiveness of the intervention.

Results: At 6-months, there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 [95% confidence interval, CI: 4.4–7.5] arbitrary units [AU], P < 0.0001), and a 93% and 98% chance of the intervention being cost-effective at a willingness-to-pay threshold of £20,000 and £30,000 per quality-adjusted life year gained.

Conclusion: The Kidney BEAM physical activity DHI is a clinically valuable and cost-effective means to improve mental health-related quality of life (HRQoL) in people with CKD (trial registration no. NCT04872933).

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