JPEM-D-16-00704_R2 Zhichao.pdf (2.75 MB)

3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials

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journal contribution
posted on 13.03.2017, 12:13 by Zhichao Chen, Xianglin Zhang, Penghua Chen, Wenchao Li, Kui Zhou, Lei Shi, Kang Liu, Changqing Liu
Recently, additive manufacturing is one of the most focused research topics due to its explosive development, especially in manufacturing engineering and medical science. In order to build 3D complex scaffolds with multi-biomaterials for clinical application, a new 3D multi-nozzle system with dual-mode drives, i.e. ejection and extrusion was developed. In this paper, much effort was made to gain fine control of droplet and excellent coordination during fabrication. Specifically, the parameters that influence the size and stability of droplet most was intensively studied. Considering that the biomaterials used in the future may have much difference in properties, the combination of parameters was investigated to facilitate the settings for certainsized droplets, which are potentially eligible for bio-printing. The dispensing nozzles can work well both in independent and convergent mode, which can be freely switched. Outstanding to the most currently used 3D bio-printing techniques, this system can fabricate scaffolds with multi-materials of both low viscosity (by pneumatic dispensing) and high viscosity (through motor extrusion). It is highly expected that this system can satisfy clinical application in the near future.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

International Journal of Precision Engineering and Manufacturing

Citation

CHEN, Z. ...et al., 2017. 3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials. International Journal of Precision Engineering and Manufacturing, 18 (5), pp.755–761.

Publisher

© Springer Verlag (Germany)

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

18/01/2017

Publication date

2017

Notes

This is a post-peer-review, pre-copyedit version of an article published in International Journal of Precision Engineering and Manufacturing. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12541-017-0090-8.

ISSN

1229-8557

Language

en

Exports