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A highly selective synthesis of the indolo[2,3-a]quinolizine ring system and application to natural product synthesis

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posted on 06.01.2006 by Steven M. Allin, Christopher I. Thomas, James E. Allard, Kevin J. Doyle, Mark Elsegood
We present a facile and highly stereoselective approach to the indolo[2,3-a]quinolizine ring system from a readily available, non-racemic chiral template. We demonstrate the potential for application of this methodology to natural product synthesis through conversion of the template to some representative indole alkaloids with high enantiomeric purity in both enantiomeric series.

History

School

  • Science

Department

  • Chemistry

Pages

291914 bytes

Citation

ALLIN, S. et al., 2005. A highly selective synthesis of the indolo[2,3-a]quinolizine ring system and application to natural product synthesis. European Journal of Organic Chemistry, 19, pp.4179-4186.

Publisher

© Wiley-VCH Verlag

Publication date

2005

Notes

This article has been published in the journal, European Journal of Organic Chemistry [© Wiley-VCH Verlag]. The definitive version, ALLIN, S. et al., 2005. A highly selective synthesis of the indolo[2,3-a]quinolizine ring system and application to natural product synthesis. European Journal of Organic Chemistry, 19, pp.4179-4186, is available at: https://doi.org/10.1002/ejoc.200500412.

ISSN

1434-193X

Language

en

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