A simple one-pot preparation of N-allenyl amides, ureas, carbamates and sulfonamides using a DMSO/tBuOK protocol
journal contributionposted on 02.03.2015 by Thomas W. Bousfield, Marc Kimber
Any type of content formally published in an academic journal, usually following a peer-review process.
A one-pot transformation of amides, ureas, carbamates and sulfonamides into synthetically useful N-allenyl analogues using a tBuOK/DMSO protocol is reported. The procedure is experimentally simple and robust, and provides N-allenyl analogues, commonly used within the literature, in yields comparable to the benchmark two-step approach.
We gratefully acknowledge financial support from the Department of Chemistry at Loughborough University.