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Associations between sedentary behaviours and cognitive function: cross-sectional and prospective findings from the UK Biobank

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posted on 31.10.2017 by Kishan Bakrania, Charlotte L. Edwardson, Kamlesh Khunti, Stephan Bandelow, Melanie J. Davies, Thomas E. Yates
We investigate the cross-sectional and prospective associations between different sedentary behaviours and cognitive function in a large sample of UK Biobank adults. Baseline data were available on 502,643 participants (years 2006-2010). Cognitive tests included prospective memory [n=171,585 (baseline only)], visual-spatial memory [round 1 (n=483,832); round 2 (n=482,762)], fluid intelligence [n=165,492], and short-term numeric memory [n=50,370]. After a mean period of 5.3-years, between 12,091 and 114,373 participants also provided follow-up cognitive data. Sedentary behaviours [Television (TV) viewing, driving, and non-occupational computer use time] were measured at baseline. At baseline, both TV viewing and driving time were inversely associated with cognitive function across all outcomes [e.g. for each additional hour spent watching TV, the total number of correct answers in the fluid intelligence test was 0.15 (99% confidence interval: 0.14, 0.16) lower]. Computer use time was positively associated with cognitive function across all outcomes. Both TV viewing and driving time at baseline were positively associated with the odds of having cognitive decline at follow-up across most outcomes. Conversely, computer use time at baseline was inversely associated with the odds of having cognitive decline at follow-up across most outcomes. This study supports health policies designed to reduce TV viewing and driving in adults.

History

School

  • Sport, Exercise and Health Sciences

Published in

American Journal of Epidemiology

Citation

BAKRANIA, K. ...et al., 2018. Associations between sedentary behaviours and cognitive function: cross-sectional and prospective findings from the UK Biobank. American Journal of Epidemiology, 187(3), pp. 441–454.

Publisher

© The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

06/07/2017

Publication date

2017-07-13

Notes

This is a pre-copyedited, author-produced version of an article accepted for publication in American Journal of Epidemiology following peer review. The version of record BAKRANIA, K. ...et al., 2018. Associations between sedentary behaviours and cognitive function: cross-sectional and prospective findings from the UK Biobank. American Journal of Epidemiology, 187(3), pp. 441–454 is available online at: https://doi.org/10.1093/aje/kwx273.

ISSN

0002-9262

eISSN

1476-6256

Language

en

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