PsyP-2007-0113-R1manuscript.pdf (261.76 kB)

Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension

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journal contribution
posted on 29.07.2014, 13:03 by Louisa Edwards, Christopher Ring, David McIntyre, John B. Winer, Una Martin
Sensorimotor deficits in patients with essential hypertension may be due to impaired nerve function. Cutaneous sensory thresholds, median nerve sensory and motor conduction velocities, andmedian nerve sensory action potential amplitudes were assessed in 30 patients with unmedicated essential hypertension and 29 normotensives. Cutaneous sensory thresholds were higher and sensory action potential amplitudes smaller in hypertensives than normotensives whereas sensory and motor nerve conduction velocities did not differ between groups. These data suggest that hypertension may reduce the number of active sensory nerve fibers without affecting myelination. Sensory action potential amplitudes were inversely related to cutaneous sensory thresholds, suggesting that subclinical axonal neuropathy of sensory afferents may help account for perceptual deficits that characterize hypertension.

History

School

  • Sport, Exercise and Health Sciences

Published in

PSYCHOPHYSIOLOGY

Volume

45

Issue

1

Pages

141 - 147 (7)

Citation

EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophysiology, 45 (1), pp. 141 - 147.

Publisher

Wiley / © Society for Psychophysiological Research

Version

AM (Accepted Manuscript)

Publication date

2008

Notes

This is the peer reviewed version of the following article: EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophsiology, 45 (1), pp. 141 - 147, which has been published in final form at: http://dx.doi.org/10.1111/j.1469-8986.2007.00608.x . This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

ISSN

0048-5772

Language

en

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