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Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis

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posted on 28.05.2019 by Martin Grootveld, Benita C. Percival, Miles Gibson, Yasan Osman, Mark Edgar, Marco Molinari, Melissa L. Mather, Federico Casanova, Philippe B. Wilson
The employment of spectroscopically-resolved NMR techniques as analytical probes have previously been both prohibitively expensive and logistically challenging in view of the large sizes of high-field facilities. However, with recent advances in the miniaturisation of magnetic resonance technology, low-field, cryogen-free “benchtop” NMR instruments are seeing wider use. Indeed, these miniaturised spectrometers are utilised in areas ranging from food and agricultural analyses, through to human biofluid assays and disease monitoring. Therefore, it is both intrinsically timely and important to highlight current applications of this analytical strategy, and also provide an outlook for the future, where this approach may be applied to a wider range of analytical problems, both qualitatively and quantitatively.

History

School

  • Science

Department

  • Chemistry

Published in

Analytica Chimica Acta

Volume

1067

Pages

11 - 30

Citation

GROOTVELD, M. ... et al., 2019. Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis. Analytica Chimica Acta, 1067, pp. 11 - 30.

Publisher

© Elsevier BV

Version

AM (Accepted Manuscript)

Publisher statement

This paper was accepted for publication in the journal Analytica Chimica Acta and the definitive published version is available at https://doi.org/10.1016/j.aca.2019.02.026.

Acceptance date

19/02/2019

Publication date

2019-02-23

ISSN

0003-2670

Language

en

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