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Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles

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posted on 30.07.2015 by Deborah Stevens, Robert Cornmell, David Taylor, Sally G. Grimshaw, Svetlana Riazanskaia, David S. Arnold, Sara J. Fernstad, Adrian M. Smith, Liam Heaney, Jim Reynolds, Paul Thomas, Mark Harker
The human foot provides an ideal environment for the colonization and growth of bacteria and subsequently is a body site associated with the liberation of odour. This study aimed to enumerate and spatially map bacterial populations’ resident across the foot to understand any association with odour production. Culture-based analysis confirmed that Staphylococci were present in higher numbers than aerobic corynebacteria and Gram-positive aerobic cocci, with all species being present at much higher levels on the plantar sites compared to dorsal sites. Microbiomic analysis supported these findings demonstrating that Staphylococcus spp. were dominant across different foot sites and comprised almost the entire bacterial population on the plantar surface. The levels of volatile fatty acids, including the key foot odour compound isovaleric acid, that contribute to foot odour were significantly increased at the plantar skin site compared to the dorsal surface. The fact that isovaleric acid was not detected on the dorsal surface but was present on the plantar surface is probably attributable to the high numbers of Staphylococcus spp. residing at this site. Variations in the spatial distribution of these microbes appear to be responsible for the localized production of odour across the foot.

History

School

  • Science

Department

  • Chemistry

Published in

FEMS MICROBIOLOGY ECOLOGY

Volume

91

Issue

1

Pages

? - ? (11)

Citation

STEVENS, D. et al., 2015. Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles. FEMS Microbiology Ecology, 91 (1), pp. 1-11.

Publisher

Oxford University Press © FEMS

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This is a pre-copyedited, author-produced PDF of an article accepted for publication in FEMS Microbiology Ecology following peer review. The version of record STEVENS, D. et al., 2015. Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles. FEMS Microbiology Ecology, 91 (1), pp. 1-11 is available online at: http://dx.doi.org/10.1093/femsec/fiu018

ISSN

0168-6496

Language

en

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