Fry et al Acta Physiol 2017 Fatigue and sensorimotor cortex oscillations.pdf (3.48 MB)
0/0

The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex

Download (3.48 MB)
journal contribution
posted on 14.03.2017 by Adam Fry, Karen J. Mullinger, George C. O'Neill, Matthew J. Brookes, Jonathan Folland
AIM: While physical fatigue is known to arise in part from supraspinal mechanisms within the brain exactly how brain activity is modulated during fatigue is not well understood. Therefore, this study examined how typical neural oscillatory responses to voluntary muscle contractions were affected by fatigue. METHODS: Eleven healthy adults (age 27±4 years) completed two experimental sessions in a randomised crossover design. Both sessions first assessed baseline maximal voluntary isometric wrist-flexion force (MVFb ). Participants then performed an identical series of fourteen test contractions (2 × 100%MVFb , 10 × 40%MVFb , 2 × 100%MVFb ) both before and after one of two interventions: forty 12-s contractions at 55%MVFb (fatigue intervention) or 5%MVFb (control intervention). Magnetoencephalography (MEG) was used to characterise both the movement-related mu and beta decrease (MRMD and MRBD) and the post-movement beta rebound (PMBR) within the contralateral sensorimotor cortex during the 40%MVFb test contractions, while the 100%MVFb test contractions were used to monitor physical fatigue. RESULTS: The fatigue intervention induced a substantial physical fatigue that endured throughout the post-intervention measurements (28.9-29.5% decrease in MVF, P<0.001). Fatigue had a significant effect on both PMBR (ANOVA, session × time-point interaction: P=0.018) and MRBD (P=0.021): the magnitude of PMBR increased following the fatigue but not the control interventions, whereas MRBD was decreased post-control but not post-fatigue. Mu oscillations were unchanged throughout both sessions. CONCLUSION: Physical fatigue resulted in an increased PMBR, and offset attenuations in MRBD associated with task habituation. This article is protected by copyright. All rights reserved.

Funding

This work was funded by a Medical Research Council New Investigator Research Grant (MR/M006301/1) awarded to funded by Medical Research Council Partnership Grant (MR/K005464/1).

History

School

  • Sport, Exercise and Health Sciences

Published in

Acta Physiologica

Citation

FRY, A. ...et al., 2016. The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex. Acta Physiologica, 220 (3), pp.370–381.

Publisher

© 2016 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

07/12/2016

Publication date

2016

Notes

This is the peer reviewed version of the following article: FRY, A. ...et al., 2016. The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex. Acta Physiologica, 220 (3), pp.370–381, which has been published in final form at http://dx.doi.org/10.1111/apha.12843. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."

eISSN

1748-1716

Language

en

Location

England

Exports