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3-Chlorooxindoles: versatile starting materials for asymmetric organocatalytic synthesis of spirooxindoles

journal contribution
posted on 2015-07-23, 09:14 authored by Artur Noole, Maksim Oseka, Tonis Pehk, Mario Oeeren, Ivar Jaerving, Mark ElsegoodMark Elsegood, Andrei MalkovAndrei Malkov, Margus Lopp, Tonis Kanger
3-Chlorooxoindoles have emerged as versatile precursors in the synthesis of spirocyclopropyl oxindoles. High enantio- and diastereoselectivity was attained under conditions of both iminium/enamine and H-bonding catalysis.

Funding

Estonian Science Foundation. Grant Number: grants no. 8289 and 8880 Ministry of Education and Research. Grant Number: 0140060s12 EU European Regional Development Fund. Grant Number: 3.2.0101.08-0017 COST-ORCA action. Grant Number: CM0905

History

School

  • Science

Department

  • Chemistry

Published in

ADVANCED SYNTHESIS & CATALYSIS

Volume

355

Issue

5

Pages

829 - 835 (7)

Citation

NOOLE, A. et al., 2013. 3-Chlorooxindoles: versatile starting materials for asymmetric organocatalytic synthesis of spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), pp. 829 - 835.

Publisher

© Wiley

Version

  • AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2013

Notes

Closed access

ISSN

1615-4150

Language

  • en