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3-Chlorooxindoles: versatile starting materials for asymmetric organocatalytic synthesis of spirooxindoles

journal contribution
posted on 23.07.2015 by Artur Noole, Maksim Oseka, Tonis Pehk, Mario Oeeren, Ivar Jaerving, Mark Elsegood, Andrei Malkov, Margus Lopp, Tonis Kanger
3-Chlorooxoindoles have emerged as versatile precursors in the synthesis of spirocyclopropyl oxindoles. High enantio- and diastereoselectivity was attained under conditions of both iminium/enamine and H-bonding catalysis.

Funding

Estonian Science Foundation. Grant Number: grants no. 8289 and 8880 Ministry of Education and Research. Grant Number: 0140060s12 EU European Regional Development Fund. Grant Number: 3.2.0101.08-0017 COST-ORCA action. Grant Number: CM0905

History

School

  • Science

Department

  • Chemistry

Published in

ADVANCED SYNTHESIS & CATALYSIS

Volume

355

Issue

5

Pages

829 - 835 (7)

Citation

NOOLE, A. et al., 2013. 3-Chlorooxindoles: versatile starting materials for asymmetric organocatalytic synthesis of spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), pp. 829 - 835.

Publisher

© Wiley

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2013

Notes

Closed access

ISSN

1615-4150

Language

en

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