posted on 2017-03-13, 12:13authored byZhichao Chen, Xianglin Zhang, Penghua Chen, Wenchao Li, Kui Zhou, Lei Shi, Kang Liu, Changqing Liu
Recently, additive manufacturing is one of the most focused research topics due to its explosive development, especially in
manufacturing engineering and medical science. In order to build 3D complex scaffolds with multi-biomaterials for clinical
application, a new 3D multi-nozzle system with dual-mode drives, i.e. ejection and extrusion was developed. In this paper,
much effort was made to gain fine control of droplet and excellent coordination during fabrication. Specifically, the parameters
that influence the size and stability of droplet most was intensively studied. Considering that the biomaterials used in the future
may have much difference in properties, the combination of parameters was investigated to facilitate the settings for certainsized
droplets, which are potentially eligible for bio-printing. The dispensing nozzles can work well both in independent and
convergent mode, which can be freely switched. Outstanding to the most currently used 3D bio-printing techniques, this system
can fabricate scaffolds with multi-materials of both low viscosity (by pneumatic dispensing) and high viscosity (through motor
extrusion). It is highly expected that this system can satisfy clinical application in the near future.
History
School
Mechanical, Electrical and Manufacturing Engineering
Published in
International Journal of Precision Engineering and Manufacturing
Volume
18
Issue
5
Pages
755 - 761
Citation
CHEN, Z. ...et al., 2017. 3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials. International Journal of Precision Engineering and Manufacturing, 18 (5), pp.755–761.
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/
Acceptance date
2017-01-31
Publication date
2017-05-09
Notes
This is a post-peer-review, pre-copyedit version of an article published in International Journal of Precision Engineering and Manufacturing. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12541-017-0090-8.