A facile and mild synthesis of enamides using a gold-catalyzed nucleophilic addition to allenamides

Kimber, Marc

A facile and mild synthesis of enamides using a gold-catalyzed nucleophilic addition to allenamides

journal contribution

posted on 2014-01-10, 13:05 authored by Marc KimberMarc Kimber

A mild and facile synthesis of enamides has been developed, based on nucleophilic addition of electron-rich aromatic and heteroaromatics to an allenamide unit catalyzed by a gold salt. Yields for the transformation were 29-98%.

History

School

Science

Department

Chemistry

Citation

KIMBER, M.C., 2010. A facile and mild synthesis of enamides using a gold-catalyzed nucleophilic addition to allenamides. Organic Letters, 12 (5), pp. 1128 - 1131

Publisher

Version

AM (Accepted Manuscript)

Publication date

2010

Notes

This article was published in the journal Organic Letters [© American Chemical Society]. The definitive version is available at: http://dx.doi.org/10.1021/ol1001494