posted on 2006-01-06, 10:29authored bySteven M. Allin, Christopher I. Thomas, James E. Allard, Kevin J. Doyle, Mark ElsegoodMark Elsegood
We present a facile and highly stereoselective approach to the indolo[2,3-a]quinolizine ring
system from a readily available, non-racemic chiral template. We demonstrate the potential for
application of this methodology to natural product synthesis through conversion of the
template to some representative indole alkaloids with high enantiomeric purity in both
enantiomeric series.
History
School
Science
Department
Chemistry
Pages
291914 bytes
Citation
ALLIN, S. et al., 2005. A highly selective synthesis of the indolo[2,3-a]quinolizine ring system and application to natural product synthesis. European Journal of Organic Chemistry, 19, pp.4179-4186.