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A hybrid approach to determining cornea mechanical properties in vivo using a combination of nano-indentation and inverse finite element analysis

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posted on 27.01.2014, 15:15 by M.H. Abyaneh, Ricky D. Wildman, Ian A. Ashcroft, Pablo RuizPablo Ruiz
An analysis of the material properties of porcine corneas has been performed. A simple stress relaxation test was performed to determine the viscoelastic properties and a rheological model was built based on the Generalized Maxwell (GM) approach. A validation experiment using nano-indentation showed that an isotropic GM model was insufficient for describing the corneal material behaviour when exposed to a complex stress state. A new technique was proposed for determining the properties, using a combination of nano-indentation experiment, an isotropic and orthotropic GM model and inverse finite element method. The good agreement using this method suggests that this is a promising technique for measuring material properties in vivo and further work should focus on the reliability of the approach in practice.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Citation

ABYANEH, M.H. ... et al, 2013. A hybrid approach to determining cornea mechanical properties in vivo using a combination of nano-indentation and inverse finite element analysis. Journal of the Mechanical Behavior of Biomedical Materials, 27, pp. 239 - 248

Publisher

© Elsevier

Version

AM (Accepted Manuscript)

Publication date

2013

Notes

This article was published in the serial, Journal of the Mechanical Behavior of Biomedical Materials [© Elsevier]. The definitive version is available at: http://dx.doi.org/10.1016/j.jmbbm.2013.05.016

ISSN

1751-6161

Language

en