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A narrative review on the potential of red beetroot as an adjuvant strategy to counter fatigue in children with cancer

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posted on 06.02.2020, 14:32 by MC Swartz, K Allen, RR Deer, EJ Lyons, MD Swartz, Tom CliffordTom Clifford
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Cancer-related fatigue (CRF) is a debilitating adverse effect among children with cancer and a significant barrier to physical activity (PA) participation. PA interventions are effective at reducing fatigue and improving both quality of life (QOL) and functional outcomes in children with cancer. However, 50–70% of children with cancer do not meet PA guidelines. Thus, adjuvant methods are needed to increase PA participation. Given the growing interest in the use of beetroot juice to reduce exercise-induced fatigue, our narrative review evaluated the potential use of beetroot to improve PA participation to counter CRF and improve QOL. Our review of 249 articles showed a lack of published clinical trials of beetroot in children and adults with cancer. Trials of beetroot use had been conducted in a noncancer population (n = 198), and anticancer studies were primarily in the preclinical phase (n = 40). Although results are promising, with beetroot juice shown to counter exercise-induced fatigue in a variety of athletic and patient populations, its use to counter CRF in children with cancer is inconclusive. Pilot and feasibility studies are needed to examine the potential benefits of beetroot to counter CRF, increase PA participation, and improve QOL in children with cancer.

History

School

  • Sport, Exercise and Health Sciences

Published in

Nutrients

Volume

11

Issue

12

Publisher

MDPI

Version

VoR (Version of Record)

Rights holder

© the Authors

Publisher statement

This is an Open Access Article. It is published by MDPI under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/

Acceptance date

06/12/2019

Publication date

2019-12-07

Copyright date

2019

ISSN

2072-6643

eISSN

2072-6643

Language

en

Depositor

Dr Tom Clifford Deposit date: 6 February 2020

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