A new asymmetric synthesis of the anti-tumour alkaloid (R)-(+)-crispine A
journal contribution
posted on 2008-01-17, 11:42authored bySteven Allin, Sean N. Gaskell, Joannah M.R. Towler, Philip C. Bulman Page, Basu Saha, Michael J. McKenzie, William P. Martin
We report a novel, facile and asymmetric approach for the synthesis of the anti-tumour alkaloid (+)-crispine A via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step.
History
School
Science
Department
Chemistry
Citation
ALLIN, S.M. ... et al., 2007. A new asymmetric synthesis of the anti-tumour alkaloid (R)-(+)-crispine A. Journal of organic chemistry, 72 (23), pp. 8972-8975