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A new asymmetric synthesis of the anti-tumour alkaloid (R)-(+)-crispine A
journal contributionposted on 2008-01-17, 11:42 authored by Steven Allin, Sean N. Gaskell, Joannah M.R. Towler, Philip C. Bulman Page, Basu Saha, Michael J. McKenzie, William P. Martin
We report a novel, facile and asymmetric approach for the synthesis of the anti-tumour alkaloid (+)-crispine A via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step.
CitationALLIN, S.M. ... et al., 2007. A new asymmetric synthesis of the anti-tumour alkaloid (R)-(+)-crispine A. Journal of organic chemistry, 72 (23), pp. 8972-8975
Publisher© American Chemical Society
NotesThis article is Restricted Access. The definitive version of this article is available at: http://pubs.acs.org/journals/joceah/index.html