Tet Lett Allenamide Paper revised.pdf (292.17 kB)
Download fileA simple one-pot preparation of N-allenyl amides, ureas, carbamates and sulfonamides using a DMSO/tBuOK protocol
journal contribution
posted on 2015-03-02, 15:12 authored by Thomas W. Bousfield, Marc KimberMarc KimberA one-pot transformation of amides, ureas, carbamates and sulfonamides into synthetically useful N-allenyl analogues using a tBuOK/DMSO protocol is reported. The procedure is experimentally simple and robust, and provides N-allenyl analogues, commonly used within the literature, in yields comparable to the benchmark two-step approach.
Funding
We gratefully acknowledge financial support from the Department of Chemistry at Loughborough University.
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